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Glossary
- ACC
- American College of Cardiology back to top
- AHA
- American Heart Association back to top
- Bare metal stent (BMS)
- A type of coronary stent that does not have a drug coating back to top
- Coronary artery lesions
- Refers to an abnormal change in the structure of the artery; development and progression of a lesion coincides with the progression of coronary artery disease back to top
- Contraindication
- something (as a symptom or condition) that makes a particular treatment or procedure potentially unsafe back to top
- Dual antiplatelet therapy (DAPT)
- The combination of aspirin and a thienopyridine/antiplatelet medication to reduce the risk of blood clots back to top
- Drug-eluting stent (DES)
- A type of coronary stent that slowly releases a drug to prevent cell growth that could otherwise contribute to the blocking of the stented artery back to top
- Double-blind trial
- A type of clinical trial in which neither the patient nor the researcher knows what treatment intervention is being administered back to top
- Investigational device exemption (IDE)
- - A regulatory milestone, approved by the FDA, which allows an device to be used in a clinical study back to top
- MACCE
- Major adverse cardiovascular and cerebrovascualr events back to top
- Myocardial ischemia
- A medical condition caused by a blockage in one or multiple heart arteries back to top
- Myocardial infarction
- The medical term for a heart attack back to top
- Open-label trial
- A type of clinical trial in which both the patient and the researcher know which treatment is being administered back to top
- Percutaneous coronary intervention (PCI)
- A therapeutic procedure used to treat narrowed blockage in the arteries of the heart, through widening a narrowed or obstructed blood vessel with a metal mesh tube, called a stent back to top
- Post-market study
- A clinical study that is conducted with medical products that have already been approved by the FDA for commercial use back to top
- Randomized trial
- A type of clinical trial that involves the random allocation of different treatment interventions to subjects back to top
- Stent
- A man made metal mesh tube that is used to open a blockage in an artery back to top
- Thienopyridine/antiplatelet medication
- A class of pharmaceuticals designed to prevent blood clots from forming back to top
- Thrombosis
- The formation of a blood clot back to top
- Trial endpoint
- In a clinical trial, a disease, symptom, or sign that constitutes one of the target outcomes of the trial back to top
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