For Patients

Glossary

ACC

ACC - American College of Cardiology back to top

AHA

American Heart Association back to top

Bare metal stent (BMS)

A type of coronary stent that does not have a drug coating back to top

Coronary artery lesions

Refers to narrowing of the artery in the heart; development and progression of a lesion coincides with the progression of coronary artery disease back to top

Contraindication

Something (as a symptom or condition) that makes a particular treatment or procedure potentially unsafe back to top

Dual antiplatelet therapy (DAPT)

The combination of aspirin and a thienopyridine/antiplatelet medication to reduce the risk of blood clots back to top

Drug-eluting stent (DES)

A type of coronary stent that slowly releases a drug to prevent cell growth that could otherwise contribute to the blocking of the stented artery back to top

Double-blind trial

A type of clinical trial in which neither the patient nor the researcher knows what treatment intervention is being administered back to top

Investigational device exemption (IDE)

A regulatory milestone, approved by the FDA, which allows an device to be used in a clinical study back to top

MACCE

Major adverse cardiovascular and cerebrovascualr events back to top

Myocardial ischemia

A medical condition caused by a blockage in one or multiple heart arteries back to top

Myocardial infarction

The medical term for a heart attack back to top

Open-label trial

A type of clinical trial in which both the patient and the researcher know which treatment is being administered back to top

Percutaneous coronary intervention (PCI)

A therapeutic procedure used to treat narrowed blockage in the arteries of the heart, through widening a narrowed or obstructed blood vessel with a metal mesh tube, called a stent back to top

Post-market study

A clinical study that is conducted with medical products that have already been approved by the FDA for commercial use back to top

Randomized trial

A type of clinical trial that involves the random allocation of different treatment interventions to subjects back to top

Stent

A man made metal mesh tube that is used to open a blockage in an artery back to top

Thienopyridine/antiplatelet medication

A class of pharmaceuticals designed to prevent blood clots from forming back to top

Thrombosis

The formation of a blood clot back to top

Trial endpoint

In a clinical trial, a disease, symptom, or sign that constitutes one of the target outcomes of the trial back to top